cd38 antibody cell signalingmultipurpose kettle uses

Human Claudin18.2-VLP (Full Length) Protein Rhesus L-Selectin Protein (ECD, Fc Tag) Human EGFR Protein (Isoform vIII, AVI & His Tag) Human IL13RA1 Protein (ECD, Fc Tag) Monkeypox Virus (MPXV) A5L Protein (His Tag) SARS-CoV-2 (BA.4/BA.5) Spike S1 Protein (His Tag) Monkeypox Virus (MPXV) A29 Antibody, Mouse MAb Monkeypox Virus (MPXV) A29 Antibody, Human Claudin18.2-VLP (Full Length) Protein Rhesus L-Selectin Protein (ECD, Fc Tag) Human EGFR Protein (Isoform vIII, AVI & His Tag) Human IL13RA1 Protein (ECD, Fc Tag) Monkeypox Virus (MPXV) A5L Protein (His Tag) SARS-CoV-2 (BA.4/BA.5) Spike S1 Protein (His Tag) Monkeypox Virus (MPXV) A29 Antibody, Mouse MAb Monkeypox Virus (MPXV) A29 Antibody, CD34 (CD34 Molecule) is a Protein Coding gene. Long-lived memory B (B MEM) cells are the basis for the recall response upon antigen reencounter either by infection or booster vaccination.They play an important role in the maintenance and evolution of the antiviral antibody response against variants, because low-affinity selection mechanisms during the germinal center reaction and continued Gene ID: 16189, updated on 27-Sep-2022. Diseases associated with RYR2 include Arrhythmogenic Right Ventricular Dysplasia, Familial, 2 and Ventricular Tachycardia, Catecholaminergic Polymorphic, 1, With Or Without Atrial Dysfunction And/Or Dilated Cardiomyopathy.Among its related pathways are Myometrial relaxation and contraction Pawlak, DeTomaso et al. WST-8 [2-(2-methoxy-4-nitrophenyl)-3-(4-nitrophenyl)-5-(2,4- disulfophenyl)-2H-tetrazolium, monosodium salt] produces a water-soluble formazan dye upon reduction in the presence of an electron mediator. These findings indicate that IL-23R functions in non-Th17 cells to drive pathogenesis during intestinal autoimmunity. Diseases associated with CD34 include Hemangiopericytoma, Malignant and Neurofibroma.Among its related pathways are Dendritic Cells Developmental Lineage Pathway and Hair follicle development: cytodifferentiation - part 3 of 3.Gene Ontology (GO) annotations related to this gene include transcription factor Tumor-induced immune suppression is the main reason for cancers evasion of immune surveillance and immune attack (1, 2).Immune checkpoint therapy (ICT) has achieved great results in the clinical treatment of some cancers, including melanoma and nonsmall cell lung cancer (NSCLC), by targeting inhibitory immune receptors such as cytotoxic T [4,5] For this reason, when treatment is indicated, systemic treatment must be considered for all patients with symptomatic plasma cell neoplasms.Patients with MGUS or asymptomatic smoldering The cancer stem cell model, also known as the Hierarchical Model proposes that tumors are hierarchically organized (CSCs lying at the apex (Fig. Usage Cited in: Cancer Lett. Image C (bottom left): Immunohistochemical analysis of ab150361 in human kidney tissue. Follicular helper T cells (TFH) are specialized to regulate multifaceted B cell responses that lead to the generation of diverse antibody-secreting plasma cells (PCs) and rapid recall-ready memory B cells (MBCs) ().Defined by their ability to migrate into the B cell follicle (), TFH orchestrate the progressive developmental decisions of class switching, germinal center Despite interesting clinical results in hematological malignancies, the development of bispecific killer-cell-engager antibody formats directed against tumor cells and stimulating anti-tumor T cell immunity has proved challenging, mostly due to toxicity problems. Cancer development and its response to therapy are regulated by inflammation, which either promotes or suppresses tumor progression, potentially displaying opposing effects on therapeutic outcomes. show that Faecalibaculum rodentium can promote epithelial proliferation and turnover by dampening retinoic acid production that supports survival of intestinal eosinophils, which in turn suppress pro-proliferative IFN- production. IL23R is a major susceptibility gene in human autoimmune diseases, but how it confers pathogenicity to T helper cells has not been fully elucidated. IL23R is a major susceptibility gene in human autoimmune diseases, but how it confers pathogenicity to T helper cells has not been fully elucidated. IDO1 (Indoleamine 2,3-Dioxygenase 1) is a Protein Coding gene. [4,5] For this reason, when treatment is indicated, systemic treatment must be considered for all patients with symptomatic plasma cell neoplasms.Patients with MGUS or asymptomatic smoldering Cross-talk between CD38 and TTP Is Essential for Resolution of Inflammation during Microbial Sepsis Cell Rep Jan 28 2020 [PMID: 31995750] (WB, Mouse) Xie W, Yin D, et al. interleukin-4, B-cell IgG differentiation factor, B-cell growth factor 1, B-cell stimulatory factor 1, IGG1 induction factor, lymphocyte stimulatory factor 1. Cao et al. The cancer stem cell model. Anti-infection Antibody-drug Conjugate/ADC Related Apoptosis Autophagy Cell Cycle/DNA Damage Cytoskeleton Epigenetics GPCR/G Protein Immunology/Inflammation JAK/STAT Signaling MAPK/ERK Pathway Membrane Transporter/Ion Channel Metabolic Enzyme/Protease Neuronal Signaling NF-B PI3K/Akt/mTOR PROTAC Protein Tyrosine GeneRIFs: Gene References Into Functions. Diseases associated with CIDEA include Body Mass Index Quantitative Trait Locus 11 and Type 2 Diabetes Mellitus.Among its related pathways are Differentiation of white and brown adipocyte and Metabolism.Gene Ontology (GO) annotations related to this gene include protein Anti-actin antibody is used as a loading control. CXCL10 (C-X-C Motif Chemokine Ligand 10) is a Protein Coding gene. Development from stem cell to B cell. Anti-actin antibody is used as a loading control. (+)-JQ-1 purchased from MCE. CXCL10 (C-X-C Motif Chemokine Ligand 10) is a Protein Coding gene. The cluster of differentiation (also known as cluster of designation or classification determinant and often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules providing targets for immunophenotyping of cells. Long-lived memory B (B MEM) cells are the basis for the recall response upon antigen reencounter either by infection or booster vaccination.They play an important role in the maintenance and evolution of the antiviral antibody response against variants, because low-affinity selection mechanisms during the germinal center reaction and continued Diseases associated with CXCL10 include Viral Meningitis and Spotted Fever.Among its related pathways are Bacterial infections in CF airways and Cytosolic sensors of pathogen-associated DNA.Gene Ontology (GO) annotations related to this gene include signaling receptor binding and This recombination is specific to the developmental stage of the B cell. ESCC cell lines are treated with 500 nM JQ1 for 48 h, whole cell lysates are analyzed by western blotting. Anti-infection Antibody-drug Conjugate/ADC Related Apoptosis Autophagy Cell Cycle/DNA Damage Cytoskeleton Epigenetics GPCR/G Protein Immunology/Inflammation JAK/STAT Signaling MAPK/ERK Pathway Membrane Transporter/Ion Channel Metabolic Enzyme/Protease Neuronal Signaling NF-B PI3K/Akt/mTOR PROTAC Protein Tyrosine Diseases associated with CIDEA include Body Mass Index Quantitative Trait Locus 11 and Type 2 Diabetes Mellitus.Among its related pathways are Differentiation of white and brown adipocyte and Metabolism.Gene Ontology (GO) annotations related to this gene include protein Over the last decade, various new therapies have been developed to promote anti-tumor immunity. Diseases associated with FABP3 include Pulmonary Embolism and Acute Myocardial Infarction.Among its related pathways are Glucose / Energy Metabolism and PPAR signaling pathway.Gene Ontology (GO) annotations related to this gene include transporter activity and cytoskeletal protein binding. B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene. Cao et al. GeneRIFs: Gene References Into Functions. Image C (bottom left): Immunohistochemical analysis of ab150361 in human kidney tissue. Enlargement of the spleen and low red blood cells (anemia) may also occur. In terms of physiology, CD molecules can act in numerous ways, often acting as receptors or ligands important to the cell. Image C (bottom left): Immunohistochemical analysis of ab150361 in human kidney tissue. demonstrate that Th1-like cells require IL-23R signaling to induce colitis. IDO1 (Indoleamine 2,3-Dioxygenase 1) is a Protein Coding gene. Later non-painful lymph node swelling, feeling tired, fever, night sweats, or weight loss for no clear reason may occur. Cell Counting Kit-8 (CCK-8) allows very convenient assays by utilizing highly water-soluble tetrazolium salt. CIDEA (Cell Death Inducing DFFA Like Effector A) is a Protein Coding gene. Diseases associated with IDO1 include Listeriosis and Bladder Disease.Among its related pathways are NAD de novo biosynthesis II (from tryptophan) and Glucose / Energy Metabolism.Gene Ontology (GO) annotations related to this gene include heme binding and tryptophan 2,3-dioxygenase activity. Later non-painful lymph node swelling, feeling tired, fever, night sweats, or weight loss for no clear reason may occur. FABP3 (Fatty Acid Binding Protein 3) is a Protein Coding gene. RYR2 (Ryanodine Receptor 2) is a Protein Coding gene. Development from stem cell to B cell. Diseases associated with CD34 include Hemangiopericytoma, Malignant and Neurofibroma.Among its related pathways are Dendritic Cells Developmental Lineage Pathway and Hair follicle development: cytodifferentiation - part 3 of 3.Gene Ontology (GO) annotations related to this gene include transcription factor Diseases associated with CIDEA include Body Mass Index Quantitative Trait Locus 11 and Type 2 Diabetes Mellitus.Among its related pathways are Differentiation of white and brown adipocyte and Metabolism.Gene Ontology (GO) annotations related to this gene include protein FABP3 (Fatty Acid Binding Protein 3) is a Protein Coding gene. The antibody treatments effectively depleted T cells, as evidenced by the loss of CD4 + and CD8 + T cell populations in spleen, lymph node (LN), and tumor, and abrogated the difference in tumor growth between Pomc-knockdown and control mice (Fig. In terms of physiology, CD molecules can act in numerous ways, often acting as receptors or ligands important to the cell. This recombination is specific to the developmental stage of the B cell. Antibodydrug conjugate (ADC) is typically composed of a monoclonal antibody (mAbs) covalently attached to a cytotoxic drug via a chemical linker. RYR2 (Ryanodine Receptor 2) is a Protein Coding gene. Park J et al. The intestinal epithelium is a central node for communication between the microbiota and immune system. Throughout each stage of development the antibody locus a site where an antigen interacts with the cell undergoes genetic recombination. CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene.CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 and signal-regulatory protein alpha (). Chronic lymphocytic leukemia (CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell). 1 TF is a P-selectin is a type-1 transmembrane protein that in humans is encoded by the SELP gene.. P-selectin functions as a cell adhesion molecule (CAM) on the surfaces of activated endothelial cells, which line the inner surface of blood vessels, and activated platelets.In unactivated endothelial cells, it is stored in granules called Weibel-Palade bodies.In unactivated platelets P Diseases associated with IDO1 include Listeriosis and Bladder Disease.Among its related pathways are NAD de novo biosynthesis II (from tryptophan) and Glucose / Energy Metabolism.Gene Ontology (GO) annotations related to this gene include heme binding and tryptophan 2,3-dioxygenase activity. [4,5] For this reason, when treatment is indicated, systemic treatment must be considered for all patients with symptomatic plasma cell neoplasms.Patients with MGUS or asymptomatic smoldering In this disorder, lymphocyte counts in the blood are usually greater than or equal to 5,000/mm 3 with a characteristic immunophenotype (CD5- and CD23-positive B cells). The cancer stem cell model. Cell Counting Kit-8 (CCK-8) allows very convenient assays by utilizing highly water-soluble tetrazolium salt. Throughout each stage of development the antibody locus a site where an antigen interacts with the cell undergoes genetic recombination. Image B (top right): Immunofluorescent analysis of ab150361 (green) in U937 cells. Within the cancer population of the tumors there are cancer stem cells (CSC) that are tumorigenic cells and are biologically distinct from other subpopulations They have two defining features: their long 2018 Apr 10;419:64-74. Cancer development and its response to therapy are regulated by inflammation, which either promotes or suppresses tumor progression, potentially displaying opposing effects on therapeutic outcomes. Evaluation of patients with monoclonal (or myeloma) protein (M protein) Idiotypic myeloma cells can be found in the blood of myeloma patients in all stages of the disease. [6,7] As assays have become more sensitive for detecting monoclonal B-CLLlike cells in peripheral blood, researchers have detected a monoclonal B-cell lymphocytosis in 3% of adults older than Monoclonal antibodies constitute a promising class of targeted anticancer agents that enhance natural immune system functions to suppress cancer cell activity and eliminate cancer cells. interleukin-4, B-cell IgG differentiation factor, B-cell growth factor 1, B-cell stimulatory factor 1, IGG1 induction factor, lymphocyte stimulatory factor 1. Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (PubMed:8478605, 14575715, 18541721).Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of View Knockout Validated Rabbit Polyclonal anti-LC3B Antibody - BSA Free. (+)-JQ-1 purchased from MCE. RYR2 (Ryanodine Receptor 2) is a Protein Coding gene. Cross-talk between CD38 and TTP Is Essential for Resolution of Inflammation during Microbial Sepsis Cell Rep Jan 28 2020 [PMID: 31995750] (WB, Mouse) Xie W, Yin D, et al. Throughout each stage of development the antibody locus a site where an antigen interacts with the cell undergoes genetic recombination. [6,7] As assays have become more sensitive for detecting monoclonal B-CLLlike cells in peripheral blood, researchers have detected a monoclonal B-cell lymphocytosis in 3% of adults older than MedChemExpress (MCE) provides 30,000+ selective Inhibitors and Recombinant Proteins with high purity and quality. 1 It is composed of Genmabs human monoclonal antibody (mAb) that binds to TF and Seagens ADC technology that utilizes a cleavable linker and the cytotoxic drug monomethyl auristatin E (MMAE). The nuclear counterstain is DAPI (blue). Usage Cited in: Cancer Lett. Diseases associated with CD34 include Hemangiopericytoma, Malignant and Neurofibroma.Among its related pathways are Dendritic Cells Developmental Lineage Pathway and Hair follicle development: cytodifferentiation - part 3 of 3.Gene Ontology (GO) annotations related to this gene include transcription factor These findings indicate that IL-23R functions in non-Th17 cells to drive pathogenesis during intestinal autoimmunity. Over the last decade, various new therapies have been developed to promote anti-tumor immunity. Diseases associated with FABP3 include Pulmonary Embolism and Acute Myocardial Infarction.Among its related pathways are Glucose / Energy Metabolism and PPAR signaling pathway.Gene Ontology (GO) annotations related to this gene include transporter activity and cytoskeletal protein binding. Over the last decade, various new therapies have been developed to promote anti-tumor immunity. Long-lived memory B (B MEM) cells are the basis for the recall response upon antigen reencounter either by infection or booster vaccination.They play an important role in the maintenance and evolution of the antiviral antibody response against variants, because low-affinity selection mechanisms during the germinal center reaction and continued Allogeneic stem cell transplantation is used only in patients with advanced and refractory disease for whom no other options are available Investigational therapies (Blood 2015;126:721): Agents target MYD88, CXCR4, BCL2, CD27 / CD70 signaling Novel proteasome inhibitors Chimeric antigen receptor modified T cell therapy CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene.CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 and signal-regulatory protein alpha (). 2E and fig. BAFF is also known as B Lymphocyte Stimulator (BLyS) and TNF- and APOL-related leukocyte expressed ligand (TALL-1) and the Dendritic cell-derived TNF-like molecule (CD257 antigen; cluster of differentiation 257). 3).) B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene. The intestinal epithelium is a central node for communication between the microbiota and immune system. Image B (top right): Immunofluorescent analysis of ab150361 (green) in U937 cells. Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (PubMed:8478605, 14575715, 18541721).Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of The nuclear counterstain is DAPI (blue). Within the cancer population of the tumors there are cancer stem cells (CSC) that are tumorigenic cells and are biologically distinct from other subpopulations They have two defining features: their long The cancer stem cell model, also known as the Hierarchical Model proposes that tumors are hierarchically organized (CSCs lying at the apex (Fig. Generation of the B cell begins in the bone marrow where stem cells give rise to lymphoid cells. 3).) Overview. CD34 (CD34 Molecule) is a Protein Coding gene. Overview. Development from stem cell to B cell. S7, B and C). WST-8 [2-(2-methoxy-4-nitrophenyl)-3-(4-nitrophenyl)-5-(2,4- disulfophenyl)-2H-tetrazolium, monosodium salt] produces a water-soluble formazan dye upon reduction in the presence of an electron mediator. FABP3 (Fatty Acid Binding Protein 3) is a Protein Coding gene. Usage Cited in: Cancer Lett. Chronic lymphocytic leukemia (CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell). demonstrate that Th1-like cells require IL-23R signaling to induce colitis. 1 It is composed of Genmabs human monoclonal antibody (mAb) that binds to TF and Seagens ADC technology that utilizes a cleavable linker and the cytotoxic drug monomethyl auristatin E (MMAE). Cell Counting Kit-8 (CCK-8) allows very convenient assays by utilizing highly water-soluble tetrazolium salt. These findings indicate that IL-23R functions in non-Th17 cells to drive pathogenesis during intestinal autoimmunity. 2018 Apr 10;419:64-74. Image A (top left): Western blot analysis of ab150361 in human bladder (lane 1), HT-1080 (lane 2), HeLa (lane 3), and U937 (lane 4) cell lysates. Tisotumab Vedotin is an antibody-drug conjugate (ADC) targeted to tissue factor (TF), a protein involved in tumor signaling and angiogenesis. Interleukin-4 receptor alpha signaling regulates monocyte homeostasis. Generation of the B cell begins in the bone marrow where stem cells give rise to lymphoid cells. Within the cancer population of the tumors there are cancer stem cells (CSC) that are tumorigenic cells and are biologically distinct from other subpopulations They have two defining features: their long Diseases associated with RYR2 include Arrhythmogenic Right Ventricular Dysplasia, Familial, 2 and Ventricular Tachycardia, Catecholaminergic Polymorphic, 1, With Or Without Atrial Dysfunction And/Or Dilated Cardiomyopathy.Among its related pathways are Myometrial relaxation and contraction Generation of the B cell begins in the bone marrow where stem cells give rise to lymphoid cells. interleukin-4, B-cell IgG differentiation factor, B-cell growth factor 1, B-cell stimulatory factor 1, IGG1 induction factor, lymphocyte stimulatory factor 1. show that Faecalibaculum rodentium can promote epithelial proliferation and turnover by dampening retinoic acid production that supports survival of intestinal eosinophils, which in turn suppress pro-proliferative IFN- production. Park J et al. Applications: WB, Simple Western, Flow, ICC/IF, IHC, KD, KO + more. This recombination is specific to the developmental stage of the B cell. GeneRIFs: Gene References Into Functions. CXCL10 (C-X-C Motif Chemokine Ligand 10) is a Protein Coding gene. BAFF is also known as B Lymphocyte Stimulator (BLyS) and TNF- and APOL-related leukocyte expressed ligand (TALL-1) and the Dendritic cell-derived TNF-like molecule (CD257 antigen; cluster of differentiation 257). 1 TF is a Tisotumab Vedotin is an antibody-drug conjugate (ADC) targeted to tissue factor (TF), a protein involved in tumor signaling and angiogenesis. Summary Other designations. In this disorder, lymphocyte counts in the blood are usually greater than or equal to 5,000/mm 3 with a characteristic immunophenotype (CD5- and CD23-positive B cells). Applications: WB, Simple Western, Flow, ICC/IF, IHC, KD, KO + more. Early on there are typically no symptoms. Human Claudin18.2-VLP (Full Length) Protein Rhesus L-Selectin Protein (ECD, Fc Tag) Human EGFR Protein (Isoform vIII, AVI & His Tag) Human IL13RA1 Protein (ECD, Fc Tag) Monkeypox Virus (MPXV) A5L Protein (His Tag) SARS-CoV-2 (BA.4/BA.5) Spike S1 Protein (His Tag) Monkeypox Virus (MPXV) A29 Antibody, Mouse MAb Monkeypox Virus (MPXV) A29 Antibody, CIDEA (Cell Death Inducing DFFA Like Effector A) is a Protein Coding gene. Diseases associated with CXCL10 include Viral Meningitis and Spotted Fever.Among its related pathways are Bacterial infections in CF airways and Cytosolic sensors of pathogen-associated DNA.Gene Ontology (GO) annotations related to this gene include signaling receptor binding and Monoclonal antibodies constitute a promising class of targeted anticancer agents that enhance natural immune system functions to suppress cancer cell activity and eliminate cancer cells. Despite interesting clinical results in hematological malignancies, the development of bispecific killer-cell-engager antibody formats directed against tumor cells and stimulating anti-tumor T cell immunity has proved challenging, mostly due to toxicity problems. Evaluation of patients with monoclonal (or myeloma) protein (M protein) Idiotypic myeloma cells can be found in the blood of myeloma patients in all stages of the disease. Allogeneic stem cell transplantation is used only in patients with advanced and refractory disease for whom no other options are available Investigational therapies (Blood 2015;126:721): Agents target MYD88, CXCR4, BCL2, CD27 / CD70 signaling Novel proteasome inhibitors Chimeric antigen receptor modified T cell therapy In this disorder, lymphocyte counts in the blood are usually greater than or equal to 5,000/mm 3 with a characteristic immunophenotype (CD5- and CD23-positive B cells). Interleukin-4 receptor alpha signaling regulates monocyte homeostasis. Pan-FGFR inhibitor, PD173074 (50 nM and 1 M), and inactive enantiomer (-)-JQ1 (4 M) are used as controls. Early on there are typically no symptoms. CD34 (CD34 Molecule) is a Protein Coding gene. Gene ID: 16189, updated on 27-Sep-2022. 3).) Follicular helper T cells (TFH) are specialized to regulate multifaceted B cell responses that lead to the generation of diverse antibody-secreting plasma cells (PCs) and rapid recall-ready memory B cells (MBCs) ().Defined by their ability to migrate into the B cell follicle (), TFH orchestrate the progressive developmental decisions of class switching, germinal center Later non-painful lymph node swelling, feeling tired, fever, night sweats, or weight loss for no clear reason may occur. View Knockout Validated Rabbit Polyclonal anti-LC3B Antibody - BSA Free. B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene. S7, B and C). Pan-FGFR inhibitor, PD173074 (50 nM and 1 M), and inactive enantiomer (-)-JQ1 (4 M) are used as controls. Evaluation of patients with monoclonal (or myeloma) protein (M protein) Idiotypic myeloma cells can be found in the blood of myeloma patients in all stages of the disease. Image A (top left): Western blot analysis of ab150361 in human bladder (lane 1), HT-1080 (lane 2), HeLa (lane 3), and U937 (lane 4) cell lysates. Summary Other designations. View Knockout Validated Rabbit Polyclonal anti-LC3B Antibody - BSA Free. Pawlak, DeTomaso et al. Image B (top right): Immunofluorescent analysis of ab150361 (green) in U937 cells. Diseases associated with FABP3 include Pulmonary Embolism and Acute Myocardial Infarction.Among its related pathways are Glucose / Energy Metabolism and PPAR signaling pathway.Gene Ontology (GO) annotations related to this gene include transporter activity and cytoskeletal protein binding.